abnormal CD8-positive, alpha beta T cell morphology_Cd8a<tm1Asin>/Cd8a<tm1Asin>,Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?

http://metadb.riken.jp/0005010I129SSvEv129S1Sv129X1SvJC57BL6JDBA2JCd8atm1AsinCd8atm1AsinRag2tm1FwaRag2tm1FwaTgTcraHYTcrbHY71VboRag2tm1FwaCd8atm1AsinTgTcraHYTcrbHY71Vbo

abnormal CD8-positive, alpha beta T cell morphology_Cd8a<tm1Asin>/Cd8a<tm1Asin>,Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• recombination activating gene 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97849
• CD8 antigen, alpha chain
  http://metadb.riken.jp/db/mgi_rdf/MGI:88346
• transgene insertion 71, Harald von Boehmer
  http://metadb.riken.jp/db/mgi_rdf/MGI:3044559

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd8a<tm1Asin>/Cd8a<tm1Asin>,Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rag2<tm1Fwa>|Cd8a<tm1Asin>|Tg(TcraH-Y,TcrbH-Y)71Vbo

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal CD8-positive, alpha beta T cell morphology
  http://purl.obolibrary.org/obo/MP_0005010

文献

http://purl.org/net/cito/citesAsAuthority

• Jung-Hyun. Park, et.al., 'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR., Nature immunology, 2007, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/17873878