decreased eosinophil cell number_Il13<tm1(YFP/cre)Lky>/Il13<+>,Il4<tm1(CD2)Mmrs>/Il4<+>,Gt(ROSA)26Sor<tm1(DTA)Lky>/Gt(ROSA)26Sor<+>

http://metadb.riken.jp/0005012I129P2OlaHsd129S4SvJaeIl13tm1YFPcreLkyIl13Il4tm1CD2MmrsIl4GtROSA26Sortm1DTALkyGtROSA26SorGtROSA26Sortm1DTALkyGtROSA26SorIl13tm1YFPcreLkyIl4Il4tm1CD2MmrsIl13

decreased eosinophil cell number_Il13<tm1(YFP/cre)Lky>/Il13<+>,Il4<tm1(CD2)Mmrs>/Il4<+>,Gt(ROSA)26Sor<tm1(DTA)Lky>/Gt(ROSA)26Sor<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• interleukin 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:96556
• interleukin 13
  http://metadb.riken.jp/db/mgi_rdf/MGI:96541

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Il13<tm1(YFP/cre)Lky>/Il13<+>,Il4<tm1(CD2)Mmrs>/Il4<+>,Gt(ROSA)26Sor<tm1(DTA)Lky>/Gt(ROSA)26Sor<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm1(DTA)Lky>|Gt(ROSA)26Sor<+>|Il13<tm1(YFP/cre)Lky>|Il4<+>|Il4<tm1(CD2)Mmrs>|Il13<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased eosinophil cell number
  http://purl.obolibrary.org/obo/MP_0005012

文献

http://purl.org/net/cito/citesAsAuthority

• Hong-Erh. Liang, et.al., Divergent expression patterns of IL-4 and IL-13 define unique functions in allergic immunity., Nature immunology, 2011, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/22138715