increased B cell number_Gt(ROSA)26Sor<tm11(Lmp1)Rsky>/Gt(ROSA)26Sor<+>,Tcrb<tm1Mom>/Tcrb<tm1Mom>,Tcrd<tm1Mom>/Tcrd<tm1Mom>,Cd19<tm1(cre)Cgn>/Cd19<+>

http://metadb.riken.jp/0005014I129P2OlaHsd129S2SvPasC57BL6GtROSA26Sortm11Lmp1RskyGtROSA26SorTcrbtm1MomTcrbtm1MomTcrdtm1MomTcrdtm1MomCd19tm1creCgnCd19GtROSA26SorGtROSA26Sortm11Lmp1RskyCd19Cd19tm1creCgnTcrbtm1MomTcrdtm1Mom

increased B cell number_Gt(ROSA)26Sor<tm11(Lmp1)Rsky>/Gt(ROSA)26Sor<+>,Tcrb<tm1Mom>/Tcrb<tm1Mom>,Tcrd<tm1Mom>/Tcrd<tm1Mom>,Cd19<tm1(cre)Cgn>/Cd19<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• T cell receptor delta chain
  http://metadb.riken.jp/db/mgi_rdf/MGI:98611
• T cell receptor beta chain
  http://metadb.riken.jp/db/mgi_rdf/MGI:98578
• CD19 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88319
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm11(Lmp1)Rsky>/Gt(ROSA)26Sor<+>,Tcrb<tm1Mom>/Tcrb<tm1Mom>,Tcrd<tm1Mom>/Tcrd<tm1Mom>,Cd19<tm1(cre)Cgn>/Cd19<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<+>|Gt(ROSA)26Sor<tm11(Lmp1)Rsky>|Cd19<+>|Cd19<tm1(cre)Cgn>|Tcrb<tm1Mom>|Tcrd<tm1Mom>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased B cell number
  http://purl.obolibrary.org/obo/MP_0005014

文献

http://purl.org/net/cito/citesAsAuthority

• Baochun. Zhang, et.al., Immune surveillance and therapy of lymphomas driven by Epstein-Barr virus protein LMP1 in a mouse model., Cell, 2012, 148
  http://rdf.ncbi.nlm.nih.gov/pubmed/22341446