increased B cell number_Igh<tm1.1(b12)Nemz>/Igh<tm1.1(b12)Nemz>,Igk<tm1.1(b12)Nemz>/Igk<tm1.1(b12)Nemz>

http://metadb.riken.jp/0005014IC57BL6NC57BL6NTacFVBNIghtm11b12NemzIghtm11b12NemzIgktm11b12NemzIgktm11b12NemzIghtm11b12NemzIgktm11b12Nemz

increased B cell number_Igh<tm1.1(b12)Nemz>/Igh<tm1.1(b12)Nemz>,Igk<tm1.1(b12)Nemz>/Igk<tm1.1(b12)Nemz>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• immunoglobulin kappa chain complex
  http://metadb.riken.jp/db/mgi_rdf/MGI:96494
• immunoglobulin heavy chain complex
  http://metadb.riken.jp/db/mgi_rdf/MGI:96442

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Igh<tm1.1(b12)Nemz>/Igh<tm1.1(b12)Nemz>,Igk<tm1.1(b12)Nemz>/Igk<tm1.1(b12)Nemz>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Igh<tm1.1(b12)Nemz>|Igk<tm1.1(b12)Nemz>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6N * C57BL/6NTac * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased B cell number
  http://purl.obolibrary.org/obo/MP_0005014

文献

http://purl.org/net/cito/citesAsAuthority

• Takayuki. Ota, et.al., B cells from knock-in mice expressing broadly neutralizing HIV antibody b12 carry an innocuous B cell receptor responsive to HIV vaccine candidates., Journal of immunology (Baltimore, Md. : 1950), 2013, 191
  http://rdf.ncbi.nlm.nih.gov/pubmed/23940273