decreased lymphocyte cell number_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Cd47<tm1Fpl>/Cd47<tm1Fpl>,Il2rg<tm1Cgn>/Y

http://metadb.riken.jp/0005016I129P2OlaHsd129SSvEv129S7SvEvBrdC57BL6Rag2tm1FwaRag2tm1FwaCd47tm1FplCd47tm1FplIl2rgtm1CgnYIl2rgtm1CgnCd47tm1FplRag2tm1Fwa

decreased lymphocyte cell number_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Cd47<tm1Fpl>/Cd47<tm1Fpl>,Il2rg<tm1Cgn>/Y

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
  http://metadb.riken.jp/db/mgi_rdf/MGI:96617
• interleukin 2 receptor, gamma chain
  http://metadb.riken.jp/db/mgi_rdf/MGI:96551
• recombination activating gene 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97849

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rag2<tm1Fwa>/Rag2<tm1Fwa>,Cd47<tm1Fpl>/Cd47<tm1Fpl>,Il2rg<tm1Cgn>/Y

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Il2rg<tm1Cgn>|Cd47<tm1Fpl>|Rag2<tm1Fwa>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S/SvEv * 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased lymphocyte cell number
  http://purl.obolibrary.org/obo/MP_0005016

文献

http://purl.org/net/cito/citesAsAuthority

• Kerry J. Lavender, et.al., BLT-humanized C57BL/6 Rag2-/-γc-/-CD47-/- mice are resistant to GVHD and develop B- and T-cell immunity to HIV infection., Blood, 2013, 122
  http://rdf.ncbi.nlm.nih.gov/pubmed/24021673