decreased B cell number_Igh-7<tm1Led>/Igh-7<tm1Led>,Lyn<tm1Ard>/Lyn<tm1Ard>

http://metadb.riken.jp/0005017I129P2OlaHsd129S4SvJaeIgh7tm1LedIgh7tm1LedLyntm1ArdLyntm1ArdLyntm1ArdIgh7tm1Led

decreased B cell number_Igh-7<tm1Led>/Igh-7<tm1Led>,Lyn<tm1Ard>/Lyn<tm1Ard>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• immunoglobulin heavy chain 7 (heavy chain of IgE)
  http://metadb.riken.jp/db/mgi_rdf/MGI:96449
• LYN proto-oncogene, Src family tyrosine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:96892

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Igh-7<tm1Led>/Igh-7<tm1Led>,Lyn<tm1Ard>/Lyn<tm1Ard>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lyn<tm1Ard>|Igh-7<tm1Led>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased B cell number
  http://purl.obolibrary.org/obo/MP_0005017

文献

http://purl.org/net/cito/citesAsAuthority

• Nicolas. Charles, et.al., Basophils and the T helper 2 environment can promote the development of lupus nephritis., Nature medicine, 2010, 16
  http://rdf.ncbi.nlm.nih.gov/pubmed/20512127