decreased B cell number_Gt(ROSA)26Sor<tm2(CAG-Notch2*)Uzs>/Gt(ROSA)26Sor<+>,Cd79a<tm1(cre)Reth>/Cd79a<+>

http://metadb.riken.jp/0005017I129S6SvEvTacBALBcC57BL6JGtROSA26Sortm2CAGNotch2UzsGtROSA26SorCd79atm1creRethCd79aGtROSA26SorCd79aGtROSA26Sortm2CAGNotch2UzsCd79atm1creReth

decreased B cell number_Gt(ROSA)26Sor<tm2(CAG-Notch2*)Uzs>/Gt(ROSA)26Sor<+>,Cd79a<tm1(cre)Reth>/Cd79a<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CD79A antigen (immunoglobulin-associated alpha)
  http://metadb.riken.jp/db/mgi_rdf/MGI:101774
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm2(CAG-Notch2*)Uzs>/Gt(ROSA)26Sor<+>,Cd79a<tm1(cre)Reth>/Cd79a<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<+>|Cd79a<+>|Gt(ROSA)26Sor<tm2(CAG-Notch2*)Uzs>|Cd79a<tm1(cre)Reth>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * BALB/c * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased B cell number
  http://purl.obolibrary.org/obo/MP_0005017

文献

http://purl.org/net/cito/citesAsAuthority

• Franziska. Hampel, et.al., CD19-independent instruction of murine marginal zone B-cell development by constitutive Notch2 signaling., Blood, 2011, 118
  http://rdf.ncbi.nlm.nih.gov/pubmed/21795747