decreased B cell number_Iglc1<tm2Ust>/Iglc1<tm2Ust>,Ptpn6<me-v>/Ptpn6<me-v>

http://metadb.riken.jp/0005017I129S7SvEvBrdC57BL6JIglc1tm2UstIglc1tm2UstPtpn6mevPtpn6mevIglc1tm2UstPtpn6mev

decreased B cell number_Iglc1<tm2Ust>/Iglc1<tm2Ust>,Ptpn6<me-v>/Ptpn6<me-v>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• immunoglobulin lambda constant 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:99546
• protein tyrosine phosphatase, non-receptor type 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:96055

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Iglc1<tm2Ust>/Iglc1<tm2Ust>,Ptpn6<me-v>/Ptpn6<me-v>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Iglc1<tm2Ust>|Ptpn6<me-v>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased B cell number
  http://purl.obolibrary.org/obo/MP_0005017

文献

http://purl.org/net/cito/citesAsAuthority

• Veronica V. Volgina, et.al., Scarcity of lambda 1 B cells in mice with a single point mutation in C lambda 1 is due to a low BCR signal caused by misfolded lambda 1 light chain., Molecular immunology, 2007, 44
  http://rdf.ncbi.nlm.nih.gov/pubmed/16860389