decreased B cell number_Cd79a<tm1(cre)Reth>/Cd79a<+>,Dicer1<tm1Mmk>/Dicer1<tm1Mmk>,Tg(BCL2)22Wehi/0

http://metadb.riken.jp/0005017IBALBcC57BL6JWehiSJLJWehiCd79atm1creRethCd79aDicer1tm1MmkDicer1tm1MmkTgBCL222Wehi0Cd79aCd79atm1creRethDicer1tm1MmkTgBCL222Wehi

decreased B cell number_Cd79a<tm1(cre)Reth>/Cd79a<+>,Dicer1<tm1Mmk>/Dicer1<tm1Mmk>,Tg(BCL2)22Wehi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 22, Walter and Eliza Hall Institute of Medical Research
  http://metadb.riken.jp/db/mgi_rdf/MGI:3052829
• dicer 1, ribonuclease type III
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177178
• CD79A antigen (immunoglobulin-associated alpha)
  http://metadb.riken.jp/db/mgi_rdf/MGI:101774

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd79a<tm1(cre)Reth>/Cd79a<+>,Dicer1<tm1Mmk>/Dicer1<tm1Mmk>,Tg(BCL2)22Wehi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cd79a<+>|Cd79a<tm1(cre)Reth>|Dicer1<tm1Mmk>|Tg(BCL2)22Wehi

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: BALB/c * C57BL/6JWehi * SJL/JWehi

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased B cell number
  http://purl.obolibrary.org/obo/MP_0005017

文献

http://purl.org/net/cito/citesAsAuthority

• Sergei B. Koralov, et.al., Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage., Cell, 2008, 132
  http://rdf.ncbi.nlm.nih.gov/pubmed/18329371