decreased B cell number_Dicer1<tm1Mmk>/Dicer1<tm1Mmk>,Tg(IghelMD4)4Ccg/0,Cd79a<tm1(cre)Reth>/Cd79a<+>

http://metadb.riken.jp/0005017IBALBcDicer1tm1MmkDicer1tm1MmkTgIghelMD44Ccg0Cd79atm1creRethCd79aTgIghelMD44CcgCd79aCd79atm1creRethDicer1tm1Mmk

decreased B cell number_Dicer1<tm1Mmk>/Dicer1<tm1Mmk>,Tg(IghelMD4)4Ccg/0,Cd79a<tm1(cre)Reth>/Cd79a<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CD79A antigen (immunoglobulin-associated alpha)
  http://metadb.riken.jp/db/mgi_rdf/MGI:101774
• transgene insertion 4, Christopher C Goodnow
  http://metadb.riken.jp/db/mgi_rdf/MGI:3053738
• dicer 1, ribonuclease type III
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177178

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dicer1<tm1Mmk>/Dicer1<tm1Mmk>,Tg(IghelMD4)4Ccg/0,Cd79a<tm1(cre)Reth>/Cd79a<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(IghelMD4)4Ccg|Cd79a<+>|Cd79a<tm1(cre)Reth>|Dicer1<tm1Mmk>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: BALB/c

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased B cell number
  http://purl.obolibrary.org/obo/MP_0005017

文献

http://purl.org/net/cito/citesAsAuthority

• Sergei B. Koralov, et.al., Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage., Cell, 2008, 132
  http://rdf.ncbi.nlm.nih.gov/pubmed/18329371