decreased T cell number_Stam<tm2Sug>/Stam<tm2Sug>,Stam2<tm1Sug>/Stam2<tm1Sug>,Tg(Lck-cre)I57Jxm/0

http://metadb.riken.jp/0005018I129S4SvJaeC57BL6ICRStamtm2SugStamtm2SugStam2tm1SugStam2tm1SugTgLckcreI57Jxm0TgLckcreI57JxmStam2tm1SugStamtm2Sug

decreased T cell number_Stam<tm2Sug>/Stam<tm2Sug>,Stam2<tm1Sug>/Stam2<tm1Sug>,Tg(Lck-cre)I57Jxm/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion I57, Jamey Marth
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177579
• signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1929100
• signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1329014

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Stam<tm2Sug>/Stam<tm2Sug>,Stam2<tm1Sug>/Stam2<tm1Sug>,Tg(Lck-cre)I57Jxm/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Lck-cre)I57Jxm|Stam2<tm1Sug>|Stam<tm2Sug>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * ICR

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased T cell number
  http://purl.obolibrary.org/obo/MP_0005018

文献

http://purl.org/net/cito/citesAsAuthority

• Mitsuhiro. Yamada, et.al., Signal-transducing adaptor molecules STAM1 and STAM2 are required for T-cell development and survival., Molecular and cellular biology, 2002, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/12446783