decreased susceptibility to parasitic infection_Il6ra<tm1.1Jcbr>/Il6ra<tm1.1Jcbr>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

http://metadb.riken.jp/0005026I129P2OlaHsdC57BL6Il6ratm11JcbrIl6ratm11JcbrLyz2tm1creIfoLyz2Lyz2tm1creIfoLyz2Il6ratm11Jcbr

decreased susceptibility to parasitic infection_Il6ra<tm1.1Jcbr>/Il6ra<tm1.1Jcbr>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• interleukin 6 receptor, alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:105304
• lysozyme 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:96897

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Il6ra<tm1.1Jcbr>/Il6ra<tm1.1Jcbr>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lyz2<tm1(cre)Ifo>|Lyz2<+>|Il6ra<tm1.1Jcbr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased susceptibility to parasitic infection
  http://purl.obolibrary.org/obo/MP_0005026

文献

http://purl.org/net/cito/citesAsAuthority

• Claudia M. Wunderlich, et.al., Cutting edge: Inhibition of IL-6 trans-signaling protects from malaria-induced lethality in mice., Journal of immunology (Baltimore, Md. : 1950), 2012, 188
  http://rdf.ncbi.nlm.nih.gov/pubmed/22467660