increased susceptibility to parasitic infection_Gzma<tm1Simn>/Gzma<tm1Simn>,Gzmb<tm1Ley>/Gzmb<tm1Ley>,Prf1<tm1Sdz>/Prf1<tm1Sdz>

http://metadb.riken.jp/0005027B6CgGzmatm1SimnGzmbtm1LeyPrf1tm1SdzGzmatm1SimnGzmatm1SimnGzmbtm1LeyGzmbtm1LeyPrf1tm1SdzPrf1tm1SdzGzmbtm1LeyGzmatm1SimnPrf1tm1Sdz

increased susceptibility to parasitic infection_Gzma<tm1Simn>/Gzma<tm1Simn>,Gzmb<tm1Ley>/Gzmb<tm1Ley>,Prf1<tm1Sdz>/Prf1<tm1Sdz>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• granzyme A
  http://metadb.riken.jp/db/mgi_rdf/MGI:109266
• perforin 1 (pore forming protein)
  http://metadb.riken.jp/db/mgi_rdf/MGI:97551
• granzyme B
  http://metadb.riken.jp/db/mgi_rdf/MGI:109267

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gzma<tm1Simn>/Gzma<tm1Simn>,Gzmb<tm1Ley>/Gzmb<tm1Ley>,Prf1<tm1Sdz>/Prf1<tm1Sdz>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gzmb<tm1Ley>|Gzma<tm1Simn>|Prf1<tm1Sdz>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.Cg-Gzma<tm1Simn> Gzmb<tm1Ley> Prf1<tm1Sdz>

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to parasitic infection
  http://purl.obolibrary.org/obo/MP_0005027

文献

http://purl.org/net/cito/citesAsAuthority

• Uwe. Müller, et.al., Concerted action of perforin and granzymes is critical for the elimination of Trypanosoma cruzi from mouse tissues, but prevention of early host death is in addition dependent on the FasL/Fas pathway., European journal of immunology, 2003, 33
  http://rdf.ncbi.nlm.nih.gov/pubmed/12594834