abnormal antigen presentation via MHC class II_Cd74<tm1Liz>/Cd74<tm1Liz>,H2-DMa<tm1Luc>/H2-DMa<tm1Luc>,Tg(CD74)AR194Ayr/?

http://metadb.riken.jp/0005041I129SSvEv129S4SvJaeC57BL6JDBA2JCd74tm1LizCd74tm1LizH2DMatm1LucH2DMatm1LucTgCD74AR194AyrH2DMatm1LucCd74tm1LizTgCD74AR194Ayr

abnormal antigen presentation via MHC class II_Cd74<tm1Liz>/Cd74<tm1Liz>,H2-DMa<tm1Luc>/H2-DMa<tm1Luc>,Tg(CD74)AR194Ayr/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• histocompatibility 2, class II, locus DMa
  http://metadb.riken.jp/db/mgi_rdf/MGI:95921
• transgene insertion AR194, Alexander Y Rudensky
  http://metadb.riken.jp/db/mgi_rdf/MGI:3760405
• CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
  http://metadb.riken.jp/db/mgi_rdf/MGI:96534

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd74<tm1Liz>/Cd74<tm1Liz>,H2-DMa<tm1Luc>/H2-DMa<tm1Luc>,Tg(CD74)AR194Ayr/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• H2-DMa<tm1Luc>|Cd74<tm1Liz>|Tg(CD74)AR194Ayr

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129S4/SvJae * C57BL/6J * DBA/2J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal antigen presentation via MHC class II
  http://purl.obolibrary.org/obo/MP_0005041

文献

http://purl.org/net/cito/citesAsAuthority

• Karen. Honey, et.al., Effect of decreasing the affinity of the class II-associated invariant chain peptide on the MHC class II peptide repertoire in the presence or absence of H-2M., Journal of immunology (Baltimore, Md. : 1950), 2004, 172
  http://rdf.ncbi.nlm.nih.gov/pubmed/15034026