abnormal lysosome morphology_Cryba1<tm1.1Dbsa>/Cryba1<tm1.1Dbsa>,Tg(BEST1-cre)1Jdun/0

http://metadb.riken.jp/0005058I129S6SvEvTacC57BL6Cryba1tm11DbsaCryba1tm11DbsaTgBEST1cre1Jdun0TgBEST1cre1JdunCryba1tm11Dbsa

abnormal lysosome morphology_Cryba1<tm1.1Dbsa>/Cryba1<tm1.1Dbsa>,Tg(BEST1-cre)1Jdun/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Joshua L Dunaief
  http://metadb.riken.jp/db/mgi_rdf/MGI:4946604
• crystallin, beta A1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88518

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cryba1<tm1.1Dbsa>/Cryba1<tm1.1Dbsa>,Tg(BEST1-cre)1Jdun/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(BEST1-cre)1Jdun|Cryba1<tm1.1Dbsa>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal lysosome morphology
  http://purl.obolibrary.org/obo/MP_0005058

文献

http://purl.org/net/cito/citesAsAuthority

• Mallika. Valapala, et.al., Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling., Autophagy, 2014, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/24468901