impaired natural killer cell mediated cytotoxicity_Prf1<tm1Tsc>/Prf1<+>

http://metadb.riken.jp/0005070I129S2SvPasPrf1tm1TscPrf1Prf1Prf1tm1Tsc

impaired natural killer cell mediated cytotoxicity_Prf1<tm1Tsc>/Prf1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• perforin 1 (pore forming protein)
  http://metadb.riken.jp/db/mgi_rdf/MGI:97551

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Prf1<tm1Tsc>/Prf1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Prf1<+>|Prf1<tm1Tsc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired natural killer cell mediated cytotoxicity
  http://purl.obolibrary.org/obo/MP_0005070

文献

http://purl.org/net/cito/citesAsAuthority

• B. Lowin, et.al., A null mutation in the perforin gene impairs cytolytic T lymphocyte- and natural killer cell-mediated cytotoxicity., Proceedings of the National Academy of Sciences of the United States of America, 1994, 91
  http://rdf.ncbi.nlm.nih.gov/pubmed/7972104