impaired natural killer cell mediated cytotoxicity_Sh2d1a<tm1Cpt>/Sh2d1a<tm1Cpt>,Sh2d1b1/Sh2d1b2<tm1.1Cpt>/Sh2d1b1/Sh2d1b2<tm1.1Cpt>

http://metadb.riken.jp/0005070I129S4SvJaeBALBcJSh2d1atm1CptSh2d1atm1CptSh2d1b1Sh2d1b2tm11CptSh2d1b1Sh2d1b2tm11CptSh2d1b1Sh2d1b2tm11CptSh2d1atm1Cpt

impaired natural killer cell mediated cytotoxicity_Sh2d1a<tm1Cpt>/Sh2d1a<tm1Cpt>,Sh2d1b1/Sh2d1b2<tm1.1Cpt>/Sh2d1b1/Sh2d1b2<tm1.1Cpt>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• SH2 domain containing 1A
  http://metadb.riken.jp/db/mgi_rdf/MGI:1328352
• SH2 domain containing 1B2
  http://metadb.riken.jp/db/mgi_rdf/MGI:3622649

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sh2d1a<tm1Cpt>/Sh2d1a<tm1Cpt>,Sh2d1b1/Sh2d1b2<tm1.1Cpt>/Sh2d1b1/Sh2d1b2<tm1.1Cpt>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Sh2d1b1/Sh2d1b2<tm1.1Cpt>|Sh2d1a<tm1Cpt>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * BALB/cJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired natural killer cell mediated cytotoxicity
  http://purl.obolibrary.org/obo/MP_0005070

文献

http://purl.org/net/cito/citesAsAuthority

• Ninghai. Wang, et.al., Cutting edge: The adapters EAT-2A and -2B are positive regulators of CD244- and CD84-dependent NK cell functions in the C57BL/6 mouse., Journal of immunology (Baltimore, Md. : 1950), 2010, 185
  http://rdf.ncbi.nlm.nih.gov/pubmed/20962259