decreased cytotoxic T cell cytolysis_Gzmb<tm1Ley>/Gzmb<tm1Ley>

http://metadb.riken.jp/0005079I129S2SvPasC57BL6JGzmbtm1LeyGzmbtm1LeyGzmbtm1Ley

decreased cytotoxic T cell cytolysis_Gzmb<tm1Ley>/Gzmb<tm1Ley>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• granzyme B
  http://metadb.riken.jp/db/mgi_rdf/MGI:109267

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gzmb<tm1Ley>/Gzmb<tm1Ley>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gzmb<tm1Ley>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased cytotoxic T cell cytolysis
  http://purl.obolibrary.org/obo/MP_0005079

文献

http://purl.org/net/cito/citesAsAuthority

• J W. Heusel, et.al., Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells., Cell, 1994, 76
  http://rdf.ncbi.nlm.nih.gov/pubmed/8137431