decreased cytotoxic T cell cytolysis_Sh2d1a<tm1Pls>/Sh2d1a<tm1Pls>,Tg(TcraTcrb)1100Mjb/0

http://metadb.riken.jp/0005079I129S6SvEvTacC57BL6Sh2d1atm1PlsSh2d1atm1PlsTgTcraTcrb1100Mjb0TgTcraTcrb1100MjbSh2d1atm1Pls

decreased cytotoxic T cell cytolysis_Sh2d1a<tm1Pls>/Sh2d1a<tm1Pls>,Tg(TcraTcrb)1100Mjb/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• SH2 domain containing 1A
  http://metadb.riken.jp/db/mgi_rdf/MGI:1328352
• transgene insertion 1100, Michael J Bevan
  http://metadb.riken.jp/db/mgi_rdf/MGI:3055219

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sh2d1a<tm1Pls>/Sh2d1a<tm1Pls>,Tg(TcraTcrb)1100Mjb/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(TcraTcrb)1100Mjb|Sh2d1a<tm1Pls>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased cytotoxic T cell cytolysis
  http://purl.obolibrary.org/obo/MP_0005079

文献

http://purl.org/net/cito/citesAsAuthority

• Fang. Zhao, et.al., Positive and negative signaling through SLAM receptors regulate synapse organization and thresholds of cytolysis., Immunity, 2012, 36
  http://rdf.ncbi.nlm.nih.gov/pubmed/22683123