decreased double-negative T cell number_Fbxw7<tm1Iaai>/Fbxw7<tm1Iaai>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0005089I129SvC57BL6CBAFbxw7tm1IaaiFbxw7tm1IaaiTgMx1cre1Cgn0TgMx1cre1CgnFbxw7tm1Iaai

decreased double-negative T cell number_Fbxw7<tm1Iaai>/Fbxw7<tm1Iaai>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072
• F-box and WD-40 domain protein 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:1354695

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fbxw7<tm1Iaai>/Fbxw7<tm1Iaai>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Mx1-cre)1Cgn|Fbxw7<tm1Iaai>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased double-negative T cell number
  http://purl.obolibrary.org/obo/MP_0005089

文献

http://purl.org/net/cito/citesAsAuthority

• Benjamin J. Thompson, et.al., Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7., The Journal of experimental medicine, 2008, 205
  http://rdf.ncbi.nlm.nih.gov/pubmed/18474632