increased double-negative T cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Fas<lpr>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0

http://metadb.riken.jp/0005090I129P2OlaHsdC57BL6DBA2MRLCd19tm1creCgnCd19FaslprFastm1CgnTgCd4cre1Cwi0TgCd4cre1CwiCd19tm1creCgnFaslprFastm1CgnCd19

increased double-negative T cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Fas<lpr>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Fas (TNF receptor superfamily member 6)
  http://metadb.riken.jp/db/mgi_rdf/MGI:95484
• CD19 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88319
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd19<tm1(cre)Cgn>/Cd19<+>,Fas<lpr>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cd4-cre)1Cwi|Cd19<tm1(cre)Cgn>|Fas<lpr>|Fas<tm1Cgn>|Cd19<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * MRL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased double-negative T cell number
  http://purl.obolibrary.org/obo/MP_0005090

文献

http://purl.org/net/cito/citesAsAuthority

• Zhenyue. Hao, et.al., T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis., The Journal of experimental medicine, 2004, 199
  http://rdf.ncbi.nlm.nih.gov/pubmed/15148335