increased double-negative T cell number_Fadd<tm1Wnt>/Fadd<tm1Wnt>,Tg(Fadd)33Wnt/0,Tg(Lck-cre)I57Jxm/0,Tg(Tcra2C,Tcrb2C)1Dlo/0

http://metadb.riken.jp/0005090I129S4SvJaeC57BL6C57LCBAICRSJLFaddtm1WntFaddtm1WntTgFadd33Wnt0TgLckcreI57Jxm0TgTcra2CTcrb2C1Dlo0Faddtm1WntTgTcra2CTcrb2C1DloTgFadd33WntTgLckcreI57Jxm

increased double-negative T cell number_Fadd<tm1Wnt>/Fadd<tm1Wnt>,Tg(Fadd)33Wnt/0,Tg(Lck-cre)I57Jxm/0,Tg(Tcra2C,Tcrb2C)1Dlo/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Dennis Y Loh
  http://metadb.riken.jp/db/mgi_rdf/MGI:3621455
• Fas (TNFRSF6)-associated via death domain
  http://metadb.riken.jp/db/mgi_rdf/MGI:109324
• transgene insertion 33, Astar Winoto
  http://metadb.riken.jp/db/mgi_rdf/MGI:4358104
• transgene insertion I57, Jamey Marth
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177579

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fadd<tm1Wnt>/Fadd<tm1Wnt>,Tg(Fadd)33Wnt/0,Tg(Lck-cre)I57Jxm/0,Tg(Tcra2C,Tcrb2C)1Dlo/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Fadd<tm1Wnt>|Tg(Tcra2C,Tcrb2C)1Dlo|Tg(Fadd)33Wnt|Tg(Lck-cre)I57Jxm

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * C57L * CBA * ICR * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased double-negative T cell number
  http://purl.obolibrary.org/obo/MP_0005090

文献

http://purl.org/net/cito/citesAsAuthority

• N H. Kabra, et.al., T cell-specific FADD-deficient mice: FADD is required for early T cell development., Proceedings of the National Academy of Sciences of the United States of America, 2001, 98
  http://rdf.ncbi.nlm.nih.gov/pubmed/11353862