increased double-positive T cell number_Fbxw7<tm1Kei>/Fbxw7<tm1Kei>,Rbpj<tm1Hon>/Rbpj<tm1Hon>,Tg(Cd4-cre)1Cwi/?

http://metadb.riken.jp/0005091I129P2OlaHsdC57BL6DBA2Fbxw7tm1KeiFbxw7tm1KeiRbpjtm1HonRbpjtm1HonTgCd4cre1CwiRbpjtm1HonTgCd4cre1CwiFbxw7tm1Kei

increased double-positive T cell number_Fbxw7<tm1Kei>/Fbxw7<tm1Kei>,Rbpj<tm1Hon>/Rbpj<tm1Hon>,Tg(Cd4-cre)1Cwi/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• F-box and WD-40 domain protein 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:1354695
• recombination signal binding protein for immunoglobulin kappa J region
  http://metadb.riken.jp/db/mgi_rdf/MGI:96522
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fbxw7<tm1Kei>/Fbxw7<tm1Kei>,Rbpj<tm1Hon>/Rbpj<tm1Hon>,Tg(Cd4-cre)1Cwi/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rbpj<tm1Hon>|Tg(Cd4-cre)1Cwi|Fbxw7<tm1Kei>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased double-positive T cell number
  http://purl.obolibrary.org/obo/MP_0005091

文献

http://purl.org/net/cito/citesAsAuthority

• Ichiro. Onoyama, et.al., Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis., The Journal of experimental medicine, 2007, 204
  http://rdf.ncbi.nlm.nih.gov/pubmed/17984302