increased double-positive T cell number_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(Tcra51-11.5,Tcrb51-11.5)AR206Ayr/0

http://metadb.riken.jp/0005091I129SSvEvC57BL6C57BL6NTacDBA2Rag2tm1FwaRag2tm1FwaTgTcra51115Tcrb51115AR206Ayr0TgTcra51115Tcrb51115AR206AyrRag2tm1Fwa

increased double-positive T cell number_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(Tcra51-11.5,Tcrb51-11.5)AR206Ayr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion AR206, Alexander Y Rudensky
  http://metadb.riken.jp/db/mgi_rdf/MGI:3760393
• recombination activating gene 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97849

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(Tcra51-11.5,Tcrb51-11.5)AR206Ayr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Tcra51-11.5,Tcrb51-11.5)AR206Ayr|Rag2<tm1Fwa>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * C57BL/6 * C57BL/6NTac * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased double-positive T cell number
  http://purl.obolibrary.org/obo/MP_0005091

文献

http://purl.org/net/cito/citesAsAuthority

• P. Wong, et.al., Competition for specific intrathymic ligands limits positive selection in a TCR transgenic model of CD4+ T cell development., Journal of immunology (Baltimore, Md. : 1950), 2000, 164
  http://rdf.ncbi.nlm.nih.gov/pubmed/10843678