increased double-positive T cell number_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(Tcra5CC7,Tcrb5CC7)IWep/?,Themis<5AT161>/Themis<5AT161>

http://metadb.riken.jp/0005091I129SSvEvC57BL6Rag2tm1FwaRag2tm1FwaTgTcra5CC7Tcrb5CC7IWepThemis5AT161Themis5AT161Themis5AT161TgTcra5CC7Tcrb5CC7IWepRag2tm1Fwa

increased double-positive T cell number_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(Tcra5CC7,Tcrb5CC7)IWep/?,Themis<5AT161>/Themis<5AT161>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• thymocyte selection associated
  http://metadb.riken.jp/db/mgi_rdf/MGI:2443552
• transgene insertion I, William E Paul
  http://metadb.riken.jp/db/mgi_rdf/MGI:3761176
• recombination activating gene 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97849

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(Tcra5CC7,Tcrb5CC7)IWep/?,Themis<5AT161>/Themis<5AT161>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Themis<5AT161>|Tg(Tcra5CC7,Tcrb5CC7)IWep|Rag2<tm1Fwa>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased double-positive T cell number
  http://purl.obolibrary.org/obo/MP_0005091

文献

http://purl.org/net/cito/citesAsAuthority

• Andy L. Johnson, et.al., Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection., Nature immunology, 2009, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/19597497