increased double-positive T cell number_Fas<tm1Ach>/Fas<tm1Ach>,Tg(Lck-cre)548Jxm/?

http://metadb.riken.jp/0005091IC57BL6CBAFastm1AchFastm1AchTgLckcre548JxmFastm1AchTgLckcre548Jxm

increased double-positive T cell number_Fas<tm1Ach>/Fas<tm1Ach>,Tg(Lck-cre)548Jxm/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Fas (TNF receptor superfamily member 6)
  http://metadb.riken.jp/db/mgi_rdf/MGI:95484
• transgene insertion 548, Jamey Marth
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176198

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fas<tm1Ach>/Fas<tm1Ach>,Tg(Lck-cre)548Jxm/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Fas<tm1Ach>|Tg(Lck-cre)548Jxm

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased double-positive T cell number
  http://purl.obolibrary.org/obo/MP_0005091

文献

http://purl.org/net/cito/citesAsAuthority

• Peter B. Stranges, et.al., Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity., Immunity, 2007, 26
  http://rdf.ncbi.nlm.nih.gov/pubmed/17509906