decreased double-positive T cell number_Tcrb<tm1Mom>/Tcrb<tm1Mom>,Tcrd<tm1Mom>/Tcrd<tm1Mom>

http://metadb.riken.jp/0005092I129BALBcC57BL6Tcrbtm1MomTcrbtm1MomTcrdtm1MomTcrdtm1MomTcrdtm1MomTcrbtm1Mom

decreased double-positive T cell number_Tcrb<tm1Mom>/Tcrb<tm1Mom>,Tcrd<tm1Mom>/Tcrd<tm1Mom>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• T cell receptor delta chain
  http://metadb.riken.jp/db/mgi_rdf/MGI:98611
• T cell receptor beta chain
  http://metadb.riken.jp/db/mgi_rdf/MGI:98578

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tcrb<tm1Mom>/Tcrb<tm1Mom>,Tcrd<tm1Mom>/Tcrd<tm1Mom>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tcrd<tm1Mom>|Tcrb<tm1Mom>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * BALB/c * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased double-positive T cell number
  http://purl.obolibrary.org/obo/MP_0005092

文献

http://purl.org/net/cito/citesAsAuthority

• P. Mombaerts, et.al., Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages., Nature, 1992, 360
  http://rdf.ncbi.nlm.nih.gov/pubmed/1359428