decreased double-positive T cell number_Crebbp<tm1Jvd>/Crebbp<tm1Jvd>,Tg(MMTV-cre)4Mam/0

http://metadb.riken.jp/0005092I129C57BL6FVBCrebbptm1JvdCrebbptm1JvdTgMMTVcre4Mam0Crebbptm1JvdTgMMTVcre4Mam

decreased double-positive T cell number_Crebbp<tm1Jvd>/Crebbp<tm1Jvd>,Tg(MMTV-cre)4Mam/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CREB binding protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:1098280
• transgene insertion 4, Lothar Hennighausen
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176163

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Crebbp<tm1Jvd>/Crebbp<tm1Jvd>,Tg(MMTV-cre)4Mam/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Crebbp<tm1Jvd>|Tg(MMTV-cre)4Mam

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased double-positive T cell number
  http://purl.obolibrary.org/obo/MP_0005092

文献

http://purl.org/net/cito/citesAsAuthority

• Ningling. Kang-Decker, et.al., Loss of CBP causes T cell lymphomagenesis in synergy with p27Kip1 insufficiency., Cancer cell, 2004, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/14998493