decreased double-positive T cell number_Rbpj<tm1Hon>/Rbpj<tm1Hon>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0005092I129P2OlaHsdC57BL6CBARbpjtm1HonRbpjtm1HonTgMx1cre1Cgn0Rbpjtm1HonTgMx1cre1Cgn

decreased double-positive T cell number_Rbpj<tm1Hon>/Rbpj<tm1Hon>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072
• recombination signal binding protein for immunoglobulin kappa J region
  http://metadb.riken.jp/db/mgi_rdf/MGI:96522

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rbpj<tm1Hon>/Rbpj<tm1Hon>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rbpj<tm1Hon>|Tg(Mx1-cre)1Cgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased double-positive T cell number
  http://purl.obolibrary.org/obo/MP_0005092

文献

http://purl.org/net/cito/citesAsAuthority

• Hua. Han, et.al., Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision., International immunology, 2002, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/12039915