decreased double-positive T cell number_Hcls1<tm1Wtn>/Hcls1<tm1Wtn>,Tg(TcraH-Y,TcrbH-Y)71Vbo/0

http://metadb.riken.jp/0005092I129P2OlaHsdC57BL6JDBA2JHcls1tm1WtnHcls1tm1WtnTgTcraHYTcrbHY71Vbo0TgTcraHYTcrbHY71VboHcls1tm1Wtn

decreased double-positive T cell number_Hcls1<tm1Wtn>/Hcls1<tm1Wtn>,Tg(TcraH-Y,TcrbH-Y)71Vbo/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• hematopoietic cell specific Lyn substrate 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:104568
• transgene insertion 71, Harald von Boehmer
  http://metadb.riken.jp/db/mgi_rdf/MGI:3044559

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hcls1<tm1Wtn>/Hcls1<tm1Wtn>,Tg(TcraH-Y,TcrbH-Y)71Vbo/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(TcraH-Y,TcrbH-Y)71Vbo|Hcls1<tm1Wtn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6J * DBA/2J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased double-positive T cell number
  http://purl.obolibrary.org/obo/MP_0005092

文献

http://purl.org/net/cito/citesAsAuthority

• I. Taniuchi, et.al., Antigen-receptor induced clonal expansion and deletion of lymphocytes are impaired in mice lacking HS1 protein, a substrate of the antigen-receptor-coupled tyrosine kinases., The EMBO journal, 1995, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/7641686