decreased double-positive T cell number_Lat<tm1Les>/Lat<tm1Les>,Lcp2<tm5(Lat/Lcp2)Gak>/Lcp2<tm5(Lat/Lcp2)Gak>

http://metadb.riken.jp/0005092I129S1Sv129X1SvJLattm1LesLattm1LesLcp2tm5LatLcp2GakLcp2tm5LatLcp2GakLcp2tm5LatLcp2GakLattm1Les

decreased double-positive T cell number_Lat<tm1Les>/Lat<tm1Les>,Lcp2<tm5(Lat/Lcp2)Gak>/Lcp2<tm5(Lat/Lcp2)Gak>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• lymphocyte cytosolic protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1321402
• linker for activation of T cells
  http://metadb.riken.jp/db/mgi_rdf/MGI:1342293

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lat<tm1Les>/Lat<tm1Les>,Lcp2<tm5(Lat/Lcp2)Gak>/Lcp2<tm5(Lat/Lcp2)Gak>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lcp2<tm5(Lat/Lcp2)Gak>|Lat<tm1Les>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased double-positive T cell number
  http://purl.obolibrary.org/obo/MP_0005092

文献

http://purl.org/net/cito/citesAsAuthority

• Natalie A. Bezman, et.al., Cutting edge: rescue of pre-TCR but not mature TCR signaling in mice expressing membrane-targeted SLP-76., Journal of immunology (Baltimore, Md. : 1950), 2009, 182
  http://rdf.ncbi.nlm.nih.gov/pubmed/19380761