decreased double-positive T cell number_Ezh2<tm2Sho>/Ezh2<tm2.1Sho>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0005092I129S1SvC57BL6CBAEzh2tm2ShoEzh2tm21ShoTgMx1cre1Cgn0TgMx1cre1CgnEzh2tm2ShoEzh2tm21Sho

decreased double-positive T cell number_Ezh2<tm2Sho>/Ezh2<tm2.1Sho>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072
• enhancer of zeste 2 polycomb repressive complex 2 subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:107940

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ezh2<tm2Sho>/Ezh2<tm2.1Sho>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Mx1-cre)1Cgn|Ezh2<tm2Sho>|Ezh2<tm2.1Sho>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased double-positive T cell number
  http://purl.obolibrary.org/obo/MP_0005092

文献

http://purl.org/net/cito/citesAsAuthority

• Camille. Simon, et.al., A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia., Genes & development, 2012, 26
  http://rdf.ncbi.nlm.nih.gov/pubmed/22431509