decreased double-positive T cell number_Runx1<tm1(RUNX1)Gcg>/Runx1<tm1(RUNX1)Gcg>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0005092I129S1SvC57BL6CBARunx1tm1RUNX1GcgRunx1tm1RUNX1GcgTgMx1cre1Cgn0TgMx1cre1CgnRunx1tm1RUNX1Gcg

decreased double-positive T cell number_Runx1<tm1(RUNX1)Gcg>/Runx1<tm1(RUNX1)Gcg>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• runt related transcription factor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:99852
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Runx1<tm1(RUNX1)Gcg>/Runx1<tm1(RUNX1)Gcg>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Mx1-cre)1Cgn|Runx1<tm1(RUNX1)Gcg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased double-positive T cell number
  http://purl.obolibrary.org/obo/MP_0005092

文献

http://purl.org/net/cito/citesAsAuthority

• Hiroyuki. Kawagoe, et.al., MN1-TEL myeloid oncoprotein expressed in multipotent progenitors perturbs both myeloid and lymphoid growth and causes T-lymphoid tumors in mice., Blood, 2005, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/16081688