decreased double-positive T cell number_Fyn<tm1Rmp>/Fyn<tm1Rmp>,Lck<tm1Mak>/Lck<tm1Mak>

http://metadb.riken.jp/0005092I129S2SvPasFyntm1RmpFyntm1RmpLcktm1MakLcktm1MakLcktm1MakFyntm1Rmp

decreased double-positive T cell number_Fyn<tm1Rmp>/Fyn<tm1Rmp>,Lck<tm1Mak>/Lck<tm1Mak>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Fyn proto-oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:95602
• lymphocyte protein tyrosine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:96756

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fyn<tm1Rmp>/Fyn<tm1Rmp>,Lck<tm1Mak>/Lck<tm1Mak>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lck<tm1Mak>|Fyn<tm1Rmp>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased double-positive T cell number
  http://purl.obolibrary.org/obo/MP_0005092

文献

http://purl.org/net/cito/citesAsAuthority

• N S. van Oers, et.al., alpha beta T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases., Immunity, 1996, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/8934570