decreased double-positive T cell number_Lck<tm1Mak>/Lck<tm1Mak>

http://metadb.riken.jp/0005092I129S2SvPasLcktm1MakLcktm1MakLcktm1Mak

decreased double-positive T cell number_Lck<tm1Mak>/Lck<tm1Mak>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• lymphocyte protein tyrosine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:96756

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lck<tm1Mak>/Lck<tm1Mak>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lck<tm1Mak>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased double-positive T cell number
  http://purl.obolibrary.org/obo/MP_0005092

文献

http://purl.org/net/cito/citesAsAuthority

• A. Würch, et.al., Reduced generation but efficient TCR beta-chain selection of CD4+8+ double-positive thymocytes in mice with compromised CD3 complex signaling., Journal of immunology (Baltimore, Md. : 1950), 1999, 162
  http://rdf.ncbi.nlm.nih.gov/pubmed/10072519
• T J. Molina, et.al., Profound block in thymocyte development in mice lacking p56lck., Nature, 1992, 357
  http://rdf.ncbi.nlm.nih.gov/pubmed/1579166