decreased double-positive T cell number_Cd8b1<tm1Litt>/Cd8b1<+>,Tg(TcraH-Y,TcrbH-Y)71Vbo/0

http://metadb.riken.jp/0005092I129S4SvJaeC57BL6JDBA2Cd8b1tm1LittCd8b1TgTcraHYTcrbHY71Vbo0TgTcraHYTcrbHY71VboCd8b1tm1LittCd8b1

decreased double-positive T cell number_Cd8b1<tm1Litt>/Cd8b1<+>,Tg(TcraH-Y,TcrbH-Y)71Vbo/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 71, Harald von Boehmer
  http://metadb.riken.jp/db/mgi_rdf/MGI:3044559
• CD8 antigen, beta chain 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88347

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd8b1<tm1Litt>/Cd8b1<+>,Tg(TcraH-Y,TcrbH-Y)71Vbo/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(TcraH-Y,TcrbH-Y)71Vbo|Cd8b1<tm1Litt>|Cd8b1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6J * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased double-positive T cell number
  http://purl.obolibrary.org/obo/MP_0005092

文献

http://purl.org/net/cito/citesAsAuthority

• M E. Crooks, et.al., Disruption of T lymphocyte positive and negative selection in mice lacking the CD8 beta chain., Immunity, 1994, 1
  http://rdf.ncbi.nlm.nih.gov/pubmed/7889415