decreased double-positive T cell number_Tcf12<tm3Zhu>/Tcf12<tm3Zhu>,Tcf3<tm4Zhu>/Tcf3<tm4Zhu>,Tg(Lck-cre)#Zhu/0

http://metadb.riken.jp/0005092I129S4SvJaeC57BL6SJLJTcf12tm3ZhuTcf12tm3ZhuTcf3tm4ZhuTcf3tm4ZhuTgLckcreZhu0TgLckcreZhuTcf12tm3ZhuTcf3tm4Zhu

decreased double-positive T cell number_Tcf12<tm3Zhu>/Tcf12<tm3Zhu>,Tcf3<tm4Zhu>/Tcf3<tm4Zhu>,Tg(Lck-cre)#Zhu/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion, Yuan Zhuang
  http://metadb.riken.jp/db/mgi_rdf/MGI:3054842
• transcription factor 12
  http://metadb.riken.jp/db/mgi_rdf/MGI:101877
• transcription factor 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:98510

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tcf12<tm3Zhu>/Tcf12<tm3Zhu>,Tcf3<tm4Zhu>/Tcf3<tm4Zhu>,Tg(Lck-cre)#Zhu/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Lck-cre)#Zhu|Tcf12<tm3Zhu>|Tcf3<tm4Zhu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * SJL/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased double-positive T cell number
  http://purl.obolibrary.org/obo/MP_0005092

文献

http://purl.org/net/cito/citesAsAuthority

• Jason. Wojciechowski, et.al., E2A and HEB are required to block thymocyte proliferation prior to pre-TCR expression., Journal of immunology (Baltimore, Md. : 1950), 2007, 178
  http://rdf.ncbi.nlm.nih.gov/pubmed/17442955