decreased double-positive T cell number_Tasp1<tm1Jjdh>/Tasp1<tm1Jjdh>,Tg(Mx1-cre)1Cgn/?

http://metadb.riken.jp/0005092I129X1SvJC57BL6CBATasp1tm1JjdhTasp1tm1JjdhTgMx1cre1CgnTgMx1cre1CgnTasp1tm1Jjdh

decreased double-positive T cell number_Tasp1<tm1Jjdh>/Tasp1<tm1Jjdh>,Tg(Mx1-cre)1Cgn/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072
• taspase, threonine aspartase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1923062

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tasp1<tm1Jjdh>/Tasp1<tm1Jjdh>,Tg(Mx1-cre)1Cgn/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Mx1-cre)1Cgn|Tasp1<tm1Jjdh>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased double-positive T cell number
  http://purl.obolibrary.org/obo/MP_0005092

文献

http://purl.org/net/cito/citesAsAuthority

• Shugaku. Takeda, et.al., Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression., Genes & development, 2006, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/16951254