decreased double-positive T cell number_Ctsd<tm1.1Thre>/Ctsd<tm1.1Thre>,Tg(Nes-cre)1Kln/0

http://metadb.riken.jp/0005092IC57BL6C57BL6NSJLCtsdtm11ThreCtsdtm11ThreTgNescre1Kln0TgNescre1KlnCtsdtm11Thre

decreased double-positive T cell number_Ctsd<tm1.1Thre>/Ctsd<tm1.1Thre>,Tg(Nes-cre)1Kln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cathepsin D
  http://metadb.riken.jp/db/mgi_rdf/MGI:88562
• transgene insertion 1, Rudiger Klein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176172

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ctsd<tm1.1Thre>/Ctsd<tm1.1Thre>,Tg(Nes-cre)1Kln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Nes-cre)1Kln|Ctsd<tm1.1Thre>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * C57BL/6N * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased double-positive T cell number
  http://purl.obolibrary.org/obo/MP_0005092

文献

http://purl.org/net/cito/citesAsAuthority

• Anett. Ketscher, et.al., Neuroectoderm-specific deletion of cathepsin D in mice models human inherited neuronal ceroid lipofuscinosis type 10., Biochimie, 2016, 122
  http://rdf.ncbi.nlm.nih.gov/pubmed/26232697