decreased B cell proliferation_Hdac1<tm1.1Pmt>/Hdac1<tm1.1Pmt>,Hdac2<tm1.1Pmt>/Hdac2<tm1.1Pmt>,Tg(Fcer2a-cre)5Mbu/0

http://metadb.riken.jp/0005093I129P2OlaHsdC57BL6CBAFVBNHdac1tm11PmtHdac1tm11PmtHdac2tm11PmtHdac2tm11PmtTgFcer2acre5Mbu0Hdac2tm11PmtHdac1tm11PmtTgFcer2acre5Mbu

decreased B cell proliferation_Hdac1<tm1.1Pmt>/Hdac1<tm1.1Pmt>,Hdac2<tm1.1Pmt>/Hdac2<tm1.1Pmt>,Tg(Fcer2a-cre)5Mbu/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• histone deacetylase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1097691
• histone deacetylase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:108086
• transgene insertion 5, Meinrad Busslinger
  http://metadb.riken.jp/db/mgi_rdf/MGI:3803645

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hdac1<tm1.1Pmt>/Hdac1<tm1.1Pmt>,Hdac2<tm1.1Pmt>/Hdac2<tm1.1Pmt>,Tg(Fcer2a-cre)5Mbu/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Hdac2<tm1.1Pmt>|Hdac1<tm1.1Pmt>|Tg(Fcer2a-cre)5Mbu

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * CBA * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased B cell proliferation
  http://purl.obolibrary.org/obo/MP_0005093

文献

http://purl.org/net/cito/citesAsAuthority

• Teppei. Yamaguchi, et.al., Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression., Genes & development, 2010, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/20194438