decreased T cell proliferation_Rasgrf2<tm1Esn>/Rasgrf2<tm1Esn>,Vav1<tm1Tyb>/Vav1<tm1Tyb>

http://metadb.riken.jp/0005095I129S1Sv129S2SvPasC57BL10C57BRcdRasgrf2tm1EsnRasgrf2tm1EsnVav1tm1TybVav1tm1TybVav1tm1TybRasgrf2tm1Esn

decreased T cell proliferation_Rasgrf2<tm1Esn>/Rasgrf2<tm1Esn>,Vav1<tm1Tyb>/Vav1<tm1Tyb>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• vav 1 oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:98923
• RAS protein-specific guanine nucleotide-releasing factor 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:109137

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rasgrf2<tm1Esn>/Rasgrf2<tm1Esn>,Vav1<tm1Tyb>/Vav1<tm1Tyb>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Vav1<tm1Tyb>|Rasgrf2<tm1Esn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S2/SvPas * C57BL/10 * C57BR/cd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased T cell proliferation
  http://purl.obolibrary.org/obo/MP_0005095

文献

http://purl.org/net/cito/citesAsAuthority

• Sergio. Ruiz, et.al., RasGRF2, a guanosine nucleotide exchange factor for Ras GTPases, participates in T-cell signaling responses., Molecular and cellular biology, 2007, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/17923690