decreased T cell proliferation_Chd4<tm1.1Kge>/Chd4<tm1.2Kge>,Tg(CAG-Bgeo/GFP)21Lbe/0,Tg(Lck-cre)1Cwi/0

http://metadb.riken.jp/0005095I129S1Sv129X1SvJC57BL6SJLChd4tm11KgeChd4tm12KgeTgCAGBgeoGFP21Lbe0TgLckcre1Cwi0Chd4tm12KgeTgCAGBgeoGFP21LbeTgLckcre1CwiChd4tm11Kge

decreased T cell proliferation_Chd4<tm1.1Kge>/Chd4<tm1.2Kge>,Tg(CAG-Bgeo/GFP)21Lbe/0,Tg(Lck-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 21, Corrinne Lobe
  http://metadb.riken.jp/db/mgi_rdf/MGI:3046175
• chromodomain helicase DNA binding protein 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:1344380
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448687

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Chd4<tm1.1Kge>/Chd4<tm1.2Kge>,Tg(CAG-Bgeo/GFP)21Lbe/0,Tg(Lck-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Chd4<tm1.2Kge>|Tg(CAG-Bgeo/GFP)21Lbe|Tg(Lck-cre)1Cwi|Chd4<tm1.1Kge>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased T cell proliferation
  http://purl.obolibrary.org/obo/MP_0005095

文献

http://purl.org/net/cito/citesAsAuthority

• Christine J. Williams, et.al., The chromatin remodeler Mi-2beta is required for CD4 expression and T cell development., Immunity, 2004, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/15189737