decreased T cell proliferation_Cd28<tm1Mak>/Cd28<tm1Mak>,Tg(Cd4-cre)1Cwi/?,Traf6<tm2Ywc>/Traf6<tm2Ywc>

http://metadb.riken.jp/0005095I129S2SvPasC57BL6DBA2Cd28tm1MakCd28tm1MakTgCd4cre1CwiTraf6tm2YwcTraf6tm2YwcTgCd4cre1CwiTraf6tm2YwcCd28tm1Mak

decreased T cell proliferation_Cd28<tm1Mak>/Cd28<tm1Mak>,Tg(Cd4-cre)1Cwi/?,Traf6<tm2Ywc>/Traf6<tm2Ywc>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• TNF receptor-associated factor 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:108072
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688
• CD28 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88327

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd28<tm1Mak>/Cd28<tm1Mak>,Tg(Cd4-cre)1Cwi/?,Traf6<tm2Ywc>/Traf6<tm2Ywc>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cd4-cre)1Cwi|Traf6<tm2Ywc>|Cd28<tm1Mak>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased T cell proliferation
  http://purl.obolibrary.org/obo/MP_0005095

文献

http://purl.org/net/cito/citesAsAuthority

• Carolyn G. King, et.al., Cutting edge: requirement for TRAF6 in the induction of T cell anergy., Journal of immunology (Baltimore, Md. : 1950), 2008, 180
  http://rdf.ncbi.nlm.nih.gov/pubmed/18097000