decreased T cell proliferation_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Sos1<tm1.1Les>/Sos1<tm1.1Les>,Tg(Lck-cre)1Cwi/0

http://metadb.riken.jp/0005095I129SSvEvC57BL6Rag2tm1FwaRag2tm1FwaSos1tm11LesSos1tm11LesTgLckcre1Cwi0Rag2tm1FwaTgLckcre1CwiSos1tm11Les

decreased T cell proliferation_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Sos1<tm1.1Les>/Sos1<tm1.1Les>,Tg(Lck-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• son of sevenless homolog 1 (Drosophila)
  http://metadb.riken.jp/db/mgi_rdf/MGI:98354
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448687
• recombination activating gene 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97849

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rag2<tm1Fwa>/Rag2<tm1Fwa>,Sos1<tm1.1Les>/Sos1<tm1.1Les>,Tg(Lck-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rag2<tm1Fwa>|Tg(Lck-cre)1Cwi|Sos1<tm1.1Les>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased T cell proliferation
  http://purl.obolibrary.org/obo/MP_0005095

文献

http://purl.org/net/cito/citesAsAuthority

• Robert L. Kortum, et.al., Targeted Sos1 deletion reveals its critical role in early T-cell development., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/21746917