decreased T cell proliferation_Pdpk1<tm1Mlw>/Pdpk1<tm1Mlw>,Tg(Cd4-cre)1Cwi/0

http://metadb.riken.jp/0005095IC57BL6DBA2Pdpk1tm1MlwPdpk1tm1MlwTgCd4cre1Cwi0Pdpk1tm1MlwTgCd4cre1Cwi

decreased T cell proliferation_Pdpk1<tm1Mlw>/Pdpk1<tm1Mlw>,Tg(Cd4-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688
• 3-phosphoinositide dependent protein kinase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1338068

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pdpk1<tm1Mlw>/Pdpk1<tm1Mlw>,Tg(Cd4-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pdpk1<tm1Mlw>|Tg(Cd4-cre)1Cwi

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased T cell proliferation
  http://purl.obolibrary.org/obo/MP_0005095

文献

http://purl.org/net/cito/citesAsAuthority

• David K. Finlay, et.al., Temporal differences in the dependency on phosphoinositide-dependent kinase 1 distinguish the development of invariant Valpha14 NKT cells and conventional T cells., Journal of immunology (Baltimore, Md. : 1950), 2010, 185
  http://rdf.ncbi.nlm.nih.gov/pubmed/20944007