abnormal spinal cord ventral horn morphology_Tg(Prnp-TARDBP)96Dwc/0,Tg(Prnp-TARDBP*Q331K)31Dwc/0

http://metadb.riken.jp/0005112IC3HC57BL6TgPrnpTARDBP96Dwc0TgPrnpTARDBPQ331K31Dwc0TgPrnpTARDBPQ331K31DwcTgPrnpTARDBP96Dwc

abnormal spinal cord ventral horn morphology_Tg(Prnp-TARDBP)96Dwc/0,Tg(Prnp-TARDBP*Q331K)31Dwc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 31, Don W Cleveland
  http://metadb.riken.jp/db/mgi_rdf/MGI:5825217
• transgene insertion 96, Don W Cleveland
  http://metadb.riken.jp/db/mgi_rdf/MGI:5463116

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Prnp-TARDBP)96Dwc/0,Tg(Prnp-TARDBP*Q331K)31Dwc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Prnp-TARDBP*Q331K)31Dwc|Tg(Prnp-TARDBP)96Dwc

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C3H * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal spinal cord ventral horn morphology
  http://purl.obolibrary.org/obo/MP_0005112

文献

http://purl.org/net/cito/citesAsAuthority

• Jacqueline C. Mitchell, et.al., Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS., Acta neuropathologica communications, 2015, 3
  http://rdf.ncbi.nlm.nih.gov/pubmed/26108367