increased circulating thyroid-stimulating hormone level_Thra<tm1Ven>/Thra<tm1Ven>,Thrb<tm1Df>/Thrb<tm1Df>

http://metadb.riken.jp/0005122I129P2OlaHsd129S1Sv129X1SvJC57BL6Thratm1VenThratm1VenThrbtm1DfThrbtm1DfThrbtm1DfThratm1Ven

increased circulating thyroid-stimulating hormone level_Thra<tm1Ven>/Thra<tm1Ven>,Thrb<tm1Df>/Thrb<tm1Df>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• thyroid hormone receptor beta
  http://metadb.riken.jp/db/mgi_rdf/MGI:98743
• thyroid hormone receptor alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:98742

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Thra<tm1Ven>/Thra<tm1Ven>,Thrb<tm1Df>/Thrb<tm1Df>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Thrb<tm1Df>|Thra<tm1Ven>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating thyroid-stimulating hormone level
  http://purl.obolibrary.org/obo/MP_0005122

文献

http://purl.org/net/cito/citesAsAuthority

• Hiroko. Furumoto, et.al., An unliganded thyroid hormone beta receptor activates the cyclin D1/cyclin-dependent kinase/retinoblastoma/E2F pathway and induces pituitary tumorigenesis., Molecular and cellular biology, 2005, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/15601836