decreased cardiac muscle contractility_Tg(Myh6-Pfkfb3)7Pne/0

http://metadb.riken.jp/0005140FVBTgMyh6Pfkfb37PneTgMyh6Pfkfb37Pne0TgMyh6Pfkfb37Pne

decreased cardiac muscle contractility_Tg(Myh6-Pfkfb3)7Pne/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 7, Paul N Epstein
  http://metadb.riken.jp/db/mgi_rdf/MGI:3640529

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Myh6-Pfkfb3)7Pne/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Myh6-Pfkfb3)7Pne

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• FVB-Tg(Myh6-Pfkfb3)7Pne

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased cardiac muscle contractility
  http://purl.obolibrary.org/obo/MP_0005140

文献

http://purl.org/net/cito/citesAsAuthority

• Rajakumar V. Donthi, et.al., Cardiac expression of kinase-deficient 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase inhibits glycolysis, promotes hypertrophy, impairs myocyte function, and reduces insulin sensitivity., The Journal of biological chemistry, 2004, 279
  http://rdf.ncbi.nlm.nih.gov/pubmed/15331593