decreased cardiac muscle contractility_Actc1<tm1Jll>/Actc1<tm1Jll>,Tg(Myh6-Actg2)1Jll/0

http://metadb.riken.jp/0005140I129P2OlaHsdBlackSwissFVBNActc1tm1JllActc1tm1JllTgMyh6Actg21Jll0TgMyh6Actg21JllActc1tm1Jll

decreased cardiac muscle contractility_Actc1<tm1Jll>/Actc1<tm1Jll>,Tg(Myh6-Actg2)1Jll/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• actin, alpha, cardiac muscle 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:87905
• transgene insertion 1, James L Lessard
  http://metadb.riken.jp/db/mgi_rdf/MGI:3583997

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Actc1<tm1Jll>/Actc1<tm1Jll>,Tg(Myh6-Actg2)1Jll/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Myh6-Actg2)1Jll|Actc1<tm1Jll>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * Black Swiss * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased cardiac muscle contractility
  http://purl.obolibrary.org/obo/MP_0005140

文献

http://purl.org/net/cito/citesAsAuthority

• Anne F. Martin, et.al., Ca(2+) activation and tension cost in myofilaments from mouse hearts ectopically expressing enteric gamma-actin., American journal of physiology. Heart and circulatory physiology, 2002, 283
  http://rdf.ncbi.nlm.nih.gov/pubmed/12124211
• A. Kumar, et.al., Rescue of cardiac alpha-actin-deficient mice by enteric smooth muscle gamma-actin., Proceedings of the National Academy of Sciences of the United States of America, 1997, 94
  http://rdf.ncbi.nlm.nih.gov/pubmed/9114002