decreased cardiac muscle contractility_Smad5<tm1Huy>/Smad5<tm1.1Huy>,Tg(Tagln-cre)1Her/0

http://metadb.riken.jp/0005140I129P2OlaHsdC57BL6CD1SJLSmad5tm1HuySmad5tm11HuyTgTaglncre1Her0Smad5tm11HuyTgTaglncre1HerSmad5tm1Huy

decreased cardiac muscle contractility_Smad5<tm1Huy>/Smad5<tm1.1Huy>,Tg(Tagln-cre)1Her/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Joachim Herz
  http://metadb.riken.jp/db/mgi_rdf/MGI:2450259
• SMAD family member 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:1328787

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Smad5<tm1Huy>/Smad5<tm1.1Huy>,Tg(Tagln-cre)1Her/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Smad5<tm1.1Huy>|Tg(Tagln-cre)1Her|Smad5<tm1Huy>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * CD-1 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased cardiac muscle contractility
  http://purl.obolibrary.org/obo/MP_0005140

文献

http://purl.org/net/cito/citesAsAuthority

• Lieve. Umans, et.al., Inactivation of Smad5 in endothelial cells and smooth muscle cells demonstrates that Smad5 is required for cardiac homeostasis., The American journal of pathology, 2007, 170
  http://rdf.ncbi.nlm.nih.gov/pubmed/17456754